The Science

We don't ask you to trust us. We provide the EXACT research so you can see for yourself!

ROOTSOPHY™  Metabolic Rewire supplement bottle — natural GLP-1 support for metabolism and focus

Metabolic Rewire

Science-backed formula for metabolic health and cognitive performance

1. GLP-1 elevation, body fat reduction and metabolic outcomes in overweight adults: A randomized double-blind placebo-controlled trial

Medicina, 2026

View Study →

2. The effects of Dyglomera® (Dichrostachys glomerata extract) on body fat percentage and body weight: a randomized, double-blind, placebo-controlled clinical trial

Functional Foods in Health and Disease, 2023

View Study →

3. Efficacy of Dichrostachys glomerata supplementation on overweight and mildly obese adults' weight, mood, and health-related quality of life

Journal of Dietary Supplements, 2024

View Study →

4. Citicoline Improves Human Vigilance and Visual Working Memory: The Role of Neuronal Activation and Oxidative Stress — Al-Kuraishy HM, Al-Gareeb AI. — 500 mg/day, generic CDP-Choline, healthy adults, randomized placebo-controlled trial.

Basic and Clinical Neuroscience, 2020

View Study →

5. Anti-obesity effect of Dyglomera® is associated with activation of the AMPK signaling pathway in 3T3-L1 adipocytes and mice with high-fat diet-induced obesity

Molecules, 2022

View Study →

6. Neurocognitive effects of acute choline supplementation in low, medium and high performer healthy volunteers — Knott V, et al. — 500 mg single dose, generic CDP-Choline, healthy adults, randomized double-blind placebo-controlled trial.

Pharmacology Biochemistry and Behavior, 2015

View Study →