Rootsophy
Metabolic Rewire
$89.99
Some people can't lose weight no matter what they do.
Others can't stop eating no matter how hard they try.
Both are the same problem — your metabolism is sidetracked. It's time to rewire it back to factory settings.
Metabolic Rewire contains Dyglofit® at the exact dose used in published clinical research. In those studies Dyglofit® alone showed:*†
- NATURAL GLP-1 SUPPORT: Increased natural GLP-1 levels by up to 294.7% — the hormone that signals fullness to your brain*† [1]
- REDUCED BODY FAT: Up to 10.3% without a prescribed diet or exercise*† [1] [2]
-
REDUCED CALORIE INTAKE: Spontaneously by 16.2% —through restored appetite control*† [1]
- INCREASED FULLNESS: After meals by up to 25.6%*† [1]
- †Based on published peer-reviewed clinical studies on Dyglofit® alone, but not the finished product of Metabolic Rewire. Research was done on overweight adults, so results may vary.[1]
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary.
No stimulants. No synthetic hormones.
Your metabolism, working the way it was designed to.
Metabolic Rewire
Some people can't lose weight no matter what they do.
Others can't stop eating no matter how hard they try.
Both are the same problem — your metabolism is sidetracked. It's time to rewire it back to factory settings.
Metabolic Rewire contains Dyglofit® at the exact dose used in published clinical research. In those studies Dyglofit® alone showed:*†
- NATURAL GLP-1 SUPPORT: Increased natural GLP-1 levels by up to 294.7% — the hormone that signals fullness to your brain*† [1]
- REDUCED BODY FAT: Up to 10.3% without a prescribed diet or exercise*† [1] [2]
-
REDUCED CALORIE INTAKE: Spontaneously by 16.2% —through restored appetite control*† [1]
- INCREASED FULLNESS: After meals by up to 25.6%*† [1]
- †Based on published peer-reviewed clinical studies on Dyglofit® alone, but not the finished product of Metabolic Rewire. Research was done on overweight adults, so results may vary.[1]
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary.
No stimulants. No synthetic hormones.
Your metabolism, working the way it was designed to.
$89.99
Out of stock
After 16 Weeks
In a randomized, double-blind, placebo-controlled clinical trial published in Medicina (2026), Dyglofit® was shown to:
- Boost natural GLP-1 levels by up to 294.7%*†
- Reduce body fat by up to 10.3%*†
- Reduce daily calorie intake by 16.2% — without a prescribed diet*†
- Increase feelings of fullness by 25.6%*†
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary.
†Based on published peer-reviewed clinical studies on Dyglofit® (Dichrostachys glomerata extract) alone, not the finished product.
Take 2 capsules daily in divided dose with or without food.
For best results, take in the morning and afternoon.
No cycling required. Safe for long-term daily use. Does not contain stimulants, synthetic hormones, or habit-forming ingredients.
Frequently Asked Questions
Is Metabolic Rewire safe to take long-term?
Yes. Both key ingredients — Dyglofit® and Citicoline — have been evaluated in multiple safety and toxicology studies and are GRAS-affirmed (Generally Recognized As Safe). Metabolic Rewire contains no stimulants, synthetic hormones, or habit-forming ingredients and is formulated for daily, long-term use.*
How long until I see results?
Most people notice improved mental clarity within the first month. In clinical studies on the key ingredient Dyglofit®, measurable metabolic changes — including reductions in body fat and calorie intake — were observed the most significant results reported at 16 weeks.*†
Can I take it with other supplements or medications?
We recommend consulting your healthcare provider before combining Metabolic Rewire with any prescription medications, particularly those affecting blood sugar, appetite, or mood. As always, if you are pregnant, nursing, or have a medical condition, please speak with your doctor before starting any new supplement.
Do I need to diet or exercise for it to work?
Metabolic Rewire is designed to make healthy choices feel easier — not to replace them. In the peer-reviewed clinical trial, participants taking the key ingredient Dyglofit® experienced significant reductions in body fat and calorie intake without a prescribed diet or exercise plan.*†That said, adding healthy nutrition habits and regular movement will always amplify any wellness results and support your overall wellbeing.
Will I regain the weight if I stop taking it?
Metabolic Rewire works by supporting your body's own natural hormone production rather than replacing it. While individual experiences vary, users are not expected to experience the aggressive rebound hunger.
Is it vegetarian and vegan friendly?
Yes. Metabolic Rewire capsules are made from vegetable cellulose and contain no animal-derived ingredients.
Does it cause hair loss or other side effects?
No hair loss has been reported or associated with either ingredient in clinical trials. It's worth noting that significant caloric reduction — from any cause — can sometimes trigger temporary hair shedding (telogen effluvium), a well-documented physiological response unrelated to any specific supplement. This is temporary and typically resolves on its own. We always recommend adequate protein intake and overall nutritional support during any period of metabolic change.
In clinical trials, no serious adverse events were reported. A small number of users may experience mild, temporary digestive adjustment during the first few days as the body adapts — this typically resolves quickly.
Both key ingredients have established safety profiles.
- Dyglofit® has been evaluated in multiple safety and toxicology studies — including subchronic and genotoxicity testing — with no serious adverse events reported, and is GRAS-affirmed (Generally Recognized As Safe).†
- Citicoline is well-tolerated at studied doses lasting 12+ months.†
Metabolic Rewire contains no stimulants, synthetic hormones, or habit-forming ingredients and is formulated for daily, long-term use.†
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary. †Based on published, peer-reviewed clinical studies on the individual ingredients Dyglofit® (Dichrostachys glomerata extract) and Citicoline (CDP-Choline), not on the finished Metabolic Rewire product.
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What to Expect Each Month
Months 1-2
Month 3-4
What is Metabolic Rewire?
-
TWO Powerful Ingredients. ONE Powerful Outcome: You, Back in CONTROL.
Metabolic Rewire™ is powered by Dichrostachys Glomerata Dyglofit®— a West African botanical extract with patent-backed research supporting your body's natural GLP-1 response. It's combined with
Citicoline — a clinically studied nootropic that supports mental clarity and focus— so your brain stops working against you.
In the 2026 Medicina Journal Dyglofit® Trial, participants experienced:
- An increase in natural GLP-1 levels by up to 294.7%**
- A reduction of body fat by up to 10.3% without a prescribed diet or exercise program.**
- A spontaneous reduction of daily calorie intake 16.2% **
- An increase feeling of fullness by up to 25.6%**
**Results were perfomed on on overweight adults using Dyglofit® alone and not the finished product of Metabolic Rewire™.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary.
Metabolic Rewire works best in Month 3 and beyond.
- — Clinically studied ingredients at therapeutic doses. Take 1 capsule twice daily to match research protocol.
- — ROOTSOPHY™ uses patented ingredients when standardization is important to the research study.
FAQs
Yes. Both key ingredients — Dyglofit® and Citicoline — have been evaluated in multiple safety and toxicology studies and are GRAS-affirmed (Generally Recognized As Safe). Metabolic Rewire contains no stimulants, synthetic hormones, or habit-forming ingredients and is formulated for daily, long-term use.*
Most people noticed an improved mental clarity within the first month. In the Dyglofit® clinical studies, measurable metabolic changes — including reductions in body fat and calorie intake — were observed with consistent use, with the most significant results reported at 16 weeks.*†
We recommend consulting your healthcare provider before combining Metabolic Rewire with any prescription medications, particularly those affecting blood sugar, appetite, or mood. As always, if you are pregnant, nursing, or have a medical condition, please speak with your doctor before starting any new supplement.
No strict diet or exercise program is required. In a peer-reviewed clinical trial, participants taking the key ingredient Dyglofit® experienced significant reductions in body fat and calorie intake without a prescribed diet or exercise plan.*† That said, adding healthy nutrition habits and regular movement will always amplify your results and support your overall wellbeing. Metabolic Rewire is designed to make those healthy choices feel easier — not to replace them.
Metabolic Rewire works by supporting your body's own natural hormone production rather than replacing it. Citicoline also helps support healthier focus patterns, that may help guide a healthier lifestyle. While individual experiences vary, users are not expected to experience the aggressive rebound hunger associated with stopping Metabolic Rewire.*
No hair loss has been reported or associated with either ingredient. In clinical trials, no serious adverse events were reported. A small number of users may experience mild, temporary digestive adjustment during the first few days as the body adapts — this typically resolves quickly. Citicoline is well-tolerated even at high doses in studies lasting 12+ months.*†
Yes. Metabolic Rewire capsules are made from vegetable cellulose and contain no animal-derived ingredients.
The Root Cause Philosophy.
The Root Cause Philosophy.